Otsuka Pharmaceutical Co., Ltd.

Pharmaceuticals
January 5, 2007

Otsuka Pharmaceutical Europe and Schwarz Pharma Deutschland to Co-promote Antiplatelet Agent Pletal® in Germany

TOKYO, January 5, 2007-- Otsuka Pharmaceutical Co., Ltd. (Otsuka Pharmaceutical) today announced that Otsuka Pharma GmbH, the German affiliate of Otsuka Pharmaceutical, and German pharmaceutical company Schwarz Pharma Deutschland GmbH will launch the antiplatelet agent Pletal® in Germany on January 8, 2007. Otsuka Pharmaceutical Europe Ltd., the European subsidiary of Otsuka Pharmaceutical, and Schwarz Pharma Deutschland have already signed the co-promotion agreement for Pletal® in October last year.

In Germany, Pletal® is an oral treatment drug indicated for improvement of the maximal and pain-free walking distances in patients with intermittent claudication. Developed by Otsuka Pharmaceutical, Pletal® was launched in the Japanese market in 1988 and is marketed in 18 countries including the United States and the UK.

Intermittent claudication is characterized by leg pain that occurs after walking a certain distance. The pain, which is caused by circulatory disorders, disappears after one stops walking and rests for a while. If left untreated, the symptoms may progress and the distance one can walk will gradually shorten. Further worsening will result in pain even while at rest and can lead to limb amputation.

About 20% of Germans aged 65 or older, in other words several hundred thousands people, are said to have intermittent claudication. This drug may help improve the quality of life of those people. Clinical trials have shown significant symptomatic improvement, and treatment with Pletal® is recommended in international guidelines.

Otsuka Pharmaceutical Co., Ltd. is dedicated to contributing to the health of people around the world, based on its corporate philosophy of "Otsuka - People creating new products for better health worldwide."

Corporate Profile

Schwarz Pharma Deutschland GmbH

Established July 1, 1955
Capital € 211.1 million
Representative Managing Director Konstantin von Alvensleben
Head office Alfred-Nobel-Str. 10, 40789 Monheim, Germany
Employees 500
Business Sales of pharmaceuticals

Otsuka Pharmaceutical Europe Ltd.

Established June 24, 1998
Capital £ 61,353,400
Representative Managing Director Meguru Kajiwara
Head office Hunton House, Highbridge Business Park, Oxford Road,
Uxbridge, Middlesex, UB8 1HU, U.K
Employees 27
Business Holding company

Otsuka Pharma GmbH

Established May 7, 1998
Capital £ 25,565
Representative Managing Director Joachim J. Schulze
Head office Hochhaus am Park, Grüneburgweg 102, 60318 Frankfurt am Main, Germany
Employees 39
Business Pharmaceuticals and medical equipment

Otsuka Pharmaceutical Co., Ltd.

Established August 10, 1964
Capital ¥ 6.791 billion
Representative President Tatsuo Higuchi
Head office 2-9 Kanda-Tsukasamachi, Chiyoda-ku Tokyo 101-8535, Japan
Tel: +81-3-3292-0021
Employees 5,103
Business Manufacturing, distributing, exporting, and importing of pharmaceuticals, clinical testing equipment, medical equipment, food products, cosmetics, and other related products