12. A natural S-equol supplement alleviates hot flushes and other menopausal symptoms in equol nonproducing postmenopausal Japanese women
Aso T, Uchiyama S, Matsumura Y, Taguchi M, Nozaki M, Takamatsu K, Ishizuka B, Kubota T, Mizunuma H, Ohta H (2012)
J Womens Health (Larchmt); 21, 92-100
Menopausal symptoms: Hot flashes, neck and shoulder stiffness
Hot flashes (feeling hot, sweating, etc.), neck and shoulder stiffness, and fatigability are reported as characteristic symptoms of menopause. A study was conducted to test the effectiveness of equol against these symptoms.
Study outline and results
126 non-equol producing, post-menopausal women experiencing hot flashes, between the ages of 45 and 60, were either given 10mg/day of equol or a placebo treatment for 12 weeks.
As a result, the group that received equol treatment reported a 50% reduction in the frequency of hot flashes and an amelioration of neck and shoulder stiffness.