InnerSignal

Unique Skin Care System Based on Otsuka’s Concern for Skin Health

The key to the InnerSignal skin care system is Energy Signal AMP*, a medicated active ingredient that promotes cellular turnover. It works by boosting the energy metabolism of skin cells that have been negatively impacted by factors such as lifestyle habits and aging, and by encouraging skin rejuvenation.

Skin that’s constantly rejuvenated

Why doesn’t our skin look the same as when we were in our 20s?
As we age, cellular turnover – the skin’s power to rejuvenate itself – decelerates, leading to problems such as discoloration, dullness, and dryness.
At Otsuka Pharmaceutical, we focused on the energy metabolism of metrocytes, also known as “mother cells.”
Extensive research led to the development of Energy Signal AMP*, a unique medicated active ingredient that promotes cellular turnover by boosting the energy metabolism of metrocytes deep within the layers of the skin, generating additional energy required for the production of new skin cells. As metrocytes produce new skin cells, cellular turnover is invigorated, flooding the outer layers of the skin with fresh cells and promoting a healthy, smooth translucent complexion.

  • *Disodium adenosine phosphate OT : This ingredient is found in InnerSignal Rejuvenate Extract, Lotion, Milk, Cream, Mask, Extract Dual, Clear Up Eyes, and ONE.

Product Line-up

You can find detailed product information below.
Basic skin care products containing Energy Signal AMP

AMP Skin Care System

Product image
Quasi-drug
InnerSignal Rejuvenate Extract
Product image
Quasi-drug
InnerSignal Rejuvenate Lotion
Product image
Quasi-drug
InnerSignal Rejuvenate Milk G
Product image
Quasi-drug
InnerSignal Rejuvenate Cream G
Product image
Quasi-drug
InnerSignal Rejuvenate ONE
Product image
Quasi-drug
InnerSignal Rejuvenate Clear Up Mask
Product image
Quasi-drug
InnerSignal Rejuvenate Extract Dual
Product image
Quasi-drug
InnerSignal Rejuvenate Clear Up Eyes
Product image
InnerSignal Rejuvenate Clear Lip
Resetting the skin by properly removing makeup and dirt

Facial Cleansing, Other

Product image
InnerSignal Rejuvenate Base Soap b
Product image
InnerSignal Rejuvenate Base Foam b
Product image
InnerSignal Cleansing Oil
Product image
InnerSignal Cleansing Cream
Product image
InnerSignal UV+IR Protect Base

All products mentioned are sold in Japan.

FAQ about this product
Product Site of InnerSignal (Japanese)

Product Site of InnerSignal (Japanese)
Information on InnerSignal's unique AMP Skin Care System

Cosmedics

Promoting healthy skin based on Otsuka’s original ideas